Depo-Provera, a commonly used injectable contraceptive, is a long-acting form of birth control. Administered every three months, it offers convenience. However, mounting evidence highlights potential health risks associated with its use. Importantly, a recent study finds that Depo-Provera increases the risk of developing brain tumors known as meningiomas.
What Is Depo-Provera?
Depo-Provera is manufactured by Pfizer, Inc. It is a synthetic hormone that prevents ovulation and thickens cervical mucus to prevent pregnancy. Notably, the active ingredient is medroxyprogesterone acetate, a derivative of progesterone. Despite its effectiveness, users have reported severe side effects, sparking debates about its safety.
Health Impacts of Depo-Provera
Research reveals that long-term use of Depo-Provera may lead to various health complications. These include:
- Bone Density Loss: Depo-Provera can reduce bone density and increase the risk of osteoporosis and fractures.
- Mental Health Effects: Some users report mood swings, depression, and anxiety.
- Meningioma: A significant concern is the potential link between Depo-Provera and meningiomas.
What is a Meningioma
A meningioma is a tumor that grows from membranes surrounding the brain or spinal cord. These tumors can be asymptomatic. As such, medical monitoring and imaging is required to ensure they do not increase in size. Alternatively, meningiomas may grow and become cancerous. Consequently, more invasive treatment such as brain surgery and radiation may be required.
The Meningioma Connection
Several studies have shown a correlation between prolonged use of Depo-Provera and a heightened risk of developing meningiomas. First, a 2021 study published in Cancer Epidemiology, Biomarkers & Prevention found that high-dose exposure to progestins like medroxyprogesterone acetate are associated with an increased risk of meningiomas. Meningiomas, while often benign, can cause severe neurological symptoms such as headaches, seizures, and vision problems.
More recently, a 2024 French study found that certain progestogens are associated with an increased risk of developing meningiomas by over 400%. Importantly, medroxyprogesterone acetate, the active ingredient in Depo-Provera, is one of these progestogens. The risk increases when Depo-Provera is used beyond one year.
Legal Recourse for Depo-Provera Users
Stag Liuzza, LLC is investigating claims on behalf of individuals who have developed meningiomas after using Depo-Provera. If you are a loved one has developed a meningioma after using Depo-Provera, please contact the experienced attorneys at Stag Liuzza, LLC for a case evaluation.
